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Louisville Cardinals vs Ole Miss Rebels Odds

Louisville Cardinals at Ole Miss Rebels — College Football Week 1

Kickoff Sunday, September 6 at 6:30 PM CT · lines updated 2026-08-22 · 3 books quoting

Best available price per side

MarketSideBest priceBook
SpreadOle Miss Rebels -6.5-115FanDuel
SpreadLouisville Cardinals +6.5-105FanDuel
TotalOver 55.5-110BetMGM
TotalUnder 55.5-105FanDuel

Prices are the best available across DraftKings, FanDuel, BetMGM and Fanatics at the time of the last update. Moneylines at -200 or worse are omitted by house rule.

The books disagree on this game

Widest gap is on the total: the best price is 2.27% better than the worst across the books quoting it. That is a factual observation about prices, not a claim about who wins.

How to read this page

Every number above is the best price a bettor could get on that side, and the book posting it. Books move independently, so the best spread and the best total on the same game often sit at different books. College football is market information only here - no model runs, so nothing on this page is a rated play.

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21+. For entertainment purposes only. Not financial advice.