Cardinals vs Chargers Odds
Arizona Cardinals at Los Angeles Chargers — NFL Week 1
Kickoff Sunday, September 13 at 3:25 PM CT · lines updated 2026-08-22 · 3 books quoting
Best available price per side
| Market | Side | Best price | Book |
|---|---|---|---|
| Spread | Los Angeles Chargers -10.5 | -106 | FanDuel |
| Spread | Arizona Cardinals +10.5 | -110 | DraftKings |
| Total | Over 46.5 | -110 | DraftKings |
| Total | Under 46.5 | -110 | DraftKings |
Prices are the best available across DraftKings, FanDuel, BetMGM and Fanatics at the time of the last update. Moneylines at -200 or worse are omitted by house rule.
The books disagree on this game
Widest gap is on the spread: the best price is 1.80% better than the worst across the books quoting it. That is a factual observation about prices, not a claim about who wins.
How to read this page
Every number above is the best price a bettor could get on that side, and the book posting it. Books move independently, so the best spread and the best total on the same game often sit at different books. Player props are tracked on paper first and are not surfaced as rated plays until they clear our promotion gate.
21+. For entertainment purposes only. Not financial advice.